da li je moguca pojava lipoma na plucima?
kakva je njihova veza za oboljenjem tipa hodgi?
i da li je ovkakva vrsta oboljenja nasledna i ako jeste po kojoj liniji?
ima "malo" pitanja ali bi mi znacilo puno kada bih na njih mogao da dobijem odgovor?.
hvala unapred
lipom
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dr ivica
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Low-level chromosome 12 amplification in a primary lipoma of the lung: Evidence for a pathogenetic relationship with common adipose tissue tumors
Archives of Pathology & Laboratory Medicine, Feb 1998 by Bridge, Julia A, Roberts, Cory A, Degenhardt, Joanne, Walker, Craig, Et al
* Cytogenetic analysis of a primary lipoma of the lung removed from a 56-year-old woman revealed the presence of a supernumerary marker chromosome in all metaphase cells analyzed; namely, 47,XX,+mar. To the best of our knowledge, this is the first cytogenetic description of a primary lipoma of lung. Genetic analysis of intramuscular lipoma, atypical lipoma, and well-differentiated liposarcoma have revealed the presence of one to three supernumerary ring or giant marker chromosomes composed of chromosome 12 segments as the characteristic anomaly. The marker chromosome in the present case was shown to be composed entirely of chromosome 12 material by subsequent analysis with a chromosome 12-specific paint probe and fluorescence in situ hybridization. Thus, analogous to intramuscular lipoma, atypical lipoma, and well-differentiated liposarcoma, extra chromosome 12 material is present. These findings support a pathogenetic relationship between this lipoma of unusual anatomic location and common adipose tissue tumors.
(Arch Pathol Lab Med 1998;122:187-190)
Archives of Pathology & Laboratory Medicine, Feb 1998 by Bridge, Julia A, Roberts, Cory A, Degenhardt, Joanne, Walker, Craig, Et al
* Cytogenetic analysis of a primary lipoma of the lung removed from a 56-year-old woman revealed the presence of a supernumerary marker chromosome in all metaphase cells analyzed; namely, 47,XX,+mar. To the best of our knowledge, this is the first cytogenetic description of a primary lipoma of lung. Genetic analysis of intramuscular lipoma, atypical lipoma, and well-differentiated liposarcoma have revealed the presence of one to three supernumerary ring or giant marker chromosomes composed of chromosome 12 segments as the characteristic anomaly. The marker chromosome in the present case was shown to be composed entirely of chromosome 12 material by subsequent analysis with a chromosome 12-specific paint probe and fluorescence in situ hybridization. Thus, analogous to intramuscular lipoma, atypical lipoma, and well-differentiated liposarcoma, extra chromosome 12 material is present. These findings support a pathogenetic relationship between this lipoma of unusual anatomic location and common adipose tissue tumors.
(Arch Pathol Lab Med 1998;122:187-190)
Primarijus dr med. Ivica Zdravkovic, specijalista opste medicine
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dr ivica
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- Pridružio se: Čet Jul 27, 2006 6:20 pm
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Primarni lipom pluca je redak, a ovaj clanak objasnjava da VEOVATNO postoji hromozomska anomalija koja je udruzena sa pojavom kako lipoma, tako i liposarkoma itd. Kariotip osoba sa anomalijom upucuje na ispoljavanje u zenskoj liniji - ali ne govori o prenosivosti po muskoj ili zenskoj liniji.
U Google ukucajte "lung lipoma" i naci cete nekoliko tekstova.
U Google ukucajte "lung lipoma" i naci cete nekoliko tekstova.
Primarijus dr med. Ivica Zdravkovic, specijalista opste medicine
NEAKTIVAN, osim za savete putem Facebooka.
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